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Top-Left: AP (Anterior-Posterior) x-ray showing pathological ankle, with severely diminished tibiotalar joint space. Top-Right: AP x-ray one-month post-operatively shows good alignment of the prosthesis, as well as plate and screws used in tibial-fibular fusion Bottom-Left: Lateral x-ray showing diminished joint space Bottom-Right: Lateral view with proper alignment (anteriorly/posteriorly) and plate and screw placement Hemi arthroplasty - partial joint replacement - is an appealing alternative to a full joint replacement, when feasible. Hemi arthroplasties of the knee joint include the replacement of only one of the three knee joint-compartments, allowing the patient to maintain a more natural state, including the maintenance of the other compartments as well as the anterior and posterior cruciate ligaments. Carticel In an effort to preserve patient's natural knee joint, the Carticel surgery series is a restorative effort, wherein a cartilage biopsy is taken (termed Carticel I), and shipped to the Genzyme corporation in Boston where cartilage cells are cloned. At a later date, these cells can then be implanted (termed Carticel II) to the area where cartilage lesions are present, including the FDA cleared trochlear groove and/or femoral condyles, and/or the "off-label" retropatellar and tibial plateau surfaces. In the world-to-date there have been approximately 25,000 Carticel II surgeries. Of these cases, one in six-or-seven still go on to a traditional total joint replacement arthroplasty. When only the femoral condyle is treated, 92% of patients report a good-to-excellent result, and when other or multiple regions are treated, good-to-excellent results are realized in 75% or more cases. These are patients who otherwise would have gone on to a knee replacement. Since being trained in Carticel in 1996, and beginning to perform the technique in 1999, Dr. Grotz has performed over 200 Carticel I biopsies, in patients whose cells are now being stored for later use, and 90 Carticel II implantations. Of these, four have gone on to a traditional knee replacement and one to a hemi arthroplasty. The largest lesion treated in the world is 31 square centimeters; Dr. Grotz has successfully treated lesions up to 30 square centimeters in size. This means that even in patients wherein extensive cartilage loss is present, the knee can often be saved. The implications are substantial, as those who realize cartilage regrowth have joints more approaching normal, and often allow full return to work and sports. In contrast, patients with knee joint replacement arthroplasties are not able to run, kneel, and perform many sports. Further, joint replacements often fail at the hip in 10-20 years and in the knee at 10 or fewer years, due to either loosening or infection. When Carticel results are maximally favorable, further surgery may never be required in the treated areas. |